Evaluation of early-phase [ 18 F]-florbetaben PET acquisition in clinical routine cases

Evaluation of early-phase [18F]-florbetaben PET acquisition in clinical routine cases

OBJECTIVES In recent years several [18F]-labelled amyloid PET tracers have been developed and have obtained clinical approval. There is accumulating evidence that early (post injection) acquisitions with these tracers are equally informative as conventional blood flow and metabolism studies for diagnosis of Alzheimer's disease, but there have been few side-by-side studies. Therefore, we investi...

[ 18 F ] Fdg - Pet

(18)F-FDG-PET CT findings in a patient with early-phase cardiac sarcoidosis.

A 54-year-old man with clinically and pathologically diagnosed cutaneous, ocular and pulmonary sarcoidosis was referred to the Cardiology Department for a prolonged PR interval and intermittent advanced atrioventricular block (Picture 1A and B). Echocardiography, gallium-67 scintigraphy and cardiac magnetic resonance imaging revealed no evidence of cardiac sarcoid involvement. F-fluoro-2deoxygl...

Early detection of encephalitis with (18)F-FDG PET/CT.

Encephalitis is a relatively rare condition for which making an accurate diagnosis can be challenging. In fact, clinical features are not specific and structural imaging can be normal in a considerable number of cases. However, an early diagnosis is important as many forms of treatment are effective if started promptly. Even though recent guidelines do not recommend (18)F-FDG PET/CT for patient...

18 F-click labeling and preclinical evaluation of a new 18 F-folate for PET imaging

BACKGROUND The folate receptor (FR) is a well-established target for tumor imaging and therapy. To date, only a few 18 F-folate conjugates via 18 F-prosthetic group labeling for positron emission tomography (PET) imaging have been developed. To some extent, they all lack the optimal balance between efficient radiochemistry and favorable in vivo characteristics. METHODS A new clickable olate p...